Customized Biospecimen Collection for Biomedical Research
VitroVivo Biotech is a leading Contract Research Organisation (CRO) company which offers biospecimen collection services to meet biomedical scientist’s needs of their research project. As our team members are experienced senior PhD level molecular pathology scientists and certified pathologists, we are able to take measures for extraordinary sample quality control and provide biospecimens with the highest quality. We work closely with clients on their study design to achieve the specific objectives set for the research projects. In addition, we are positioned to perform full-scale histopathology services and other molecular biological experiments on-site. We are a professional hisopathology company you can trust for customized biospecimen collection services.
Customized Biospecimen Collection
Pure Cell Population Dissected by LCM
We provide support and services in
- Biospecimen Collection protocol development
- IRB submission
- Informed consent form customization
- Sample collection, processing and transportation
- Case report form implementation
- Sample storage under desired environment
Our clinical site for biospecimen collection is closely monitored and managed by site coordinators whose responsibilities include regular personnel training, sample collection oversight, inventory supplies and specimen logistics.
Description of Customized Biospecimen Collection Services
|Specimen Combinations||Specimens can be supplied either as individual samples or as different specimen combinations to meet various research purposes.|
|Matched Specimen Set — Same Donor Based|
|Retrospective/Archival Samples||FFPE blocks collected and stored at major clinical sites and our repository. Treatment information and clinical outcome can be provided for up to 10 years from the date of collection. Matching recurrent /metastatic tumor FFPE block can be provided upon request.|
|Prospective Sample Collection||Fresh frozen tissues, FFPE blocks, matching biofluids and other specimen formats can be procured according to Capital Bio-sciences standard collection protocols or custom developed protocols. Treatment and follow-up information can be provided for majority of prospectively collected samples.|
|FFPE Blocks and Slides|
Formalin Fixed Paraffin Embedded (FFPE) tissue block is prepared by tissue fixed in 10% neutral-buffered formalin and embedded in IHC-grade paraffin wax. Standard tissue size is 1×1×0.5 cm, but it can vary depending on the nature of the disease and tissue type. The fixation agent and the embedding media could be customized if requested. FFPE blocks are collected under VitroVivo Standard Operating Procedures (SOPs).
|Fresh Frozen Tissue and Slides|
Fresh frozen tissue samples collected by certified medical pathologists are snap-frozen in liquid nitrogen within 30 minutes of surgical excision. Sample can be collected into OCT embedding media upon request. Standard sample weight is 0.5 – 1 gram. Fresh frozen tissue samples are collected under VitroViVo Standard Operating Procedures (SOPs)
VitroVivo Biotech provides various biological fluids under standard collection protocols or with modified protocols if it is for custom procurement projects.
|Blood||VitroVivo Biotech can supply up to 15 ml of whole blood from one donor. Standard Blood samples are collected into 4-8 ml K2 EDTA tube (anti-coagulation agent can be changed upon request).|
|Bone Marrow||Bone Marrow is from patients with hematological malignancies. Standard sample is collected as 0.5-1 ml snap-frozen aspirate. Bone marrow smear on a glass microscopic slide can be provided upon request.|
|Other Biofluids||Serum, Plasma, Urine, Saliva, Synovial and Cerebrospinal Fluid|
|Pure cells dissected by LCM||VitroVivo provides some customized pure cell population which are microdissected by ArcturusXT™ LCM system.|
Inquiries and Orders
Please fill out the Customized Biospecimen Collection Service Request Form below and enter as much detail as possible. VitroVivo will conduct a quick feasibility study and get back to you with information on availability, time duration and pricing within 24 hours.