Tissue Array

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Microarray Panel Adrenal gland tumor tissue microarray, containing 34 cases of adrenal cortical adenomas, 10 adrenal cortical adenocarcinoma, 3 neuroblastoma, 1 ganglioneuroma, 30 pheochromocytoma, 4 hyperplasia, 6 adjacent normal tissue and 8 adrenal tissue, duplicate cores per case
Cores 192
Cases 96
Row number 12
Column number 16
Core Diameter (mm) 1
Thickness (µm) 5
Tissue Array Type FFPE
Species Human
Applications Routine histology procedures including Immunohistochemistry (IHC) and In Situ Hybridization (ISH), protocols which can be found at our support page.
Notes 1. TMA slides were sectioned and stored at 4°C and may not be fresh cut, but still suitable for IHC. Please request fresh cut if experiment involves phospho-specific antibodies, RNA studies, FISH or ISH, etc. A minimum of 3 slides per TMA must be purchased to cover the cost of trimming for fresh sectioning.
2. Most TMA slides were not coated with an extra layer of paraffin (tissue cores can be easily seen on the glass). To prevent tissue detachment during antigen retrieval, unbaked slides must be baked for at least 30 to 120 minutes at 60°C. before putting into xylene for de-paraffinization. Baked slides were sent out baked for 2 hours.
In the following specsheet,“*” means invalid core; “-” means no applicable or negative in IHC markers.

 

Description Bladder cancer (stage III-IV) tissue array, including TNM and clinical stage, 60 cases/60 cores, replacing BL601b
Total cases 60                  
Total array cores 60                  
Array panel Bladder carcinoma tissue microarray, containing 60 cases of urothelial carcinoma, single core per case  
Array core diameter 1.5                  
Section thickness 5                  
Quality control: H&E and IHC confirmed              
Row number 6                  
Column number 10                  
                     

 

  1 2 3 4 5 6 7 8 9 10
A TU Tu Tu Tu Tu Tu Tu Tu Tu Tu
B Tu Tu Tu Tu Tu Tu Tu Tu Tu Tu
C Tu Tu Tu Tu Tu Tu Tu Tu Tu Tu
D Tu Tu Tu Tu Tu Tu Tu Tu Tu Tu
E Tu Tu Tu Tu Tu Tu Tu Tu Tu Tu
F Tu Tu Tu Tu Tu Tu Tu Tu Tu Tu
 

 

 Detailed Information of Tissue Array Panel

No. Position Age Sex Organ/Anatomic Site Pathology diagnosis TNM Stage Type    
1 A1 42 F Bladder Invasive urothelial carcinoma T3N0M0 III Malignant    
2 A2 72 M Bladder Invasive urothelial carcinoma T3N0M0 III Malignant    
3 A3 66 M Bladder Invasive urothelial carcinoma T3N0M0 III Malignant    
4 A4 62 M Bladder Invasive urothelial carcinoma T3N0M0 III Malignant    
5 A5 80 M Bladder Invasive urothelial carcinoma T3N0M0 III Malignant    
6 A6 75 M Bladder Invasive urothelial carcinoma T3N0M0 III Malignant    
7 A7 72 M Bladder Invasive urothelial carcinoma T3N0M0 III Malignant    
8 A8 54 F Bladder Invasive urothelial carcinoma T3N0M0 III Malignant    
9 A9 70 M Bladder Invasive urothelial carcinoma T3N0M0 III Malignant    
10 A10 67 F Bladder Invasive urothelial carcinoma T3N0M0 III Malignant    
11 B1 75 F Bladder Invasive urothelial carcinoma T3N0M0 III Malignant    
12 B2 65 M Bladder Invasive urothelial carcinoma T3N0M0 III Malignant    
13 B3 58 M Bladder Invasive urothelial carcinoma T3N0M0 III Malignant    
14 B4 67 M Bladder Invasive urothelial carcinoma T3N0M0 III Malignant    
15 B5 67 M Bladder Invasive urothelial carcinoma T3N0M0 III Malignant    
16 B6 65 M Bladder Invasive urothelial carcinoma T3N0M0 III Malignant    
17 B7 74 M Bladder Invasive urothelial carcinoma T4N0M0 III Malignant    
18 B8 57 M Bladder Invasive urothelial carcinoma T3N0M0 III Malignant    
19 B9 67 M Bladder Invasive urothelial carcinoma T3N0M0 III Malignant    
20 B10 62 M Bladder Invasive urothelial carcinoma T3N0M0 III Malignant    
21 C1 72 M Bladder Invasive urothelial carcinoma T3N0M0 III Malignant    
22 C2 78 M Bladder Invasive urothelial carcinoma T3N0M0 III Malignant    
23 C3 38 M Bladder Invasive urothelial carcinoma T3N0M0 III Malignant    
24 C4 68 M Bladder Invasive urothelial carcinoma T3N0M0 III Malignant    
25 C5 65 F Bladder Invasive urothelial carcinoma T3N0M0 III Malignant    
26 C6 66 M Bladder Invasive urothelial carcinoma T3N0M0 III Malignant    
27 C7 64 M Bladder Invasive urothelial carcinoma T3N0M0 III Malignant    
28 C8 86 M Bladder Invasive urothelial carcinoma T3N0M0 III Malignant    
29 C9 60 M Bladder Invasive urothelial carcinoma T3N0M0 III Malignant    
30 C10 42 M Bladder Invasive urothelial carcinoma T3N0M0 III Malignant    
31 D1 54 M Bladder Invasive urothelial carcinoma T3N0M0 III Malignant    
32 D2 71 F Bladder Invasive urothelial carcinoma T3N0M0 III Malignant    
33 D3 60 F Bladder Invasive urothelial carcinoma T3N0M0 III Malignant    
34 D4 73 M Bladder Invasive urothelial carcinoma T3N0M0 III Malignant    
35 D5 74 M Bladder Invasive urothelial carcinoma T3N0M0 III Malignant    
36 D6 70 M Bladder Invasive urothelial carcinoma T3N0M0 III Malignant    
37 D7 54 F Bladder Invasive urothelial carcinoma T2N0M0 III Malignant    
38 D8 58 M Bladder Invasive urothelial carcinoma T3N0M0 III Malignant    
39 D9 65 F Bladder Invasive urothelial carcinoma T3N0M0 III Malignant    
40 D10 60 M Bladder Invasive urothelial carcinoma T3N0M0 III Malignant    
41 E1 60 M Bladder Invasive urothelial carcinoma T3N0M0 III Malignant    
42 E2 70 F Bladder Invasive urothelial carcinoma T3N0M0 III Malignant    
43 E3 65 F Bladder Invasive urothelial carcinoma T3N0M0 III Malignant    
44 E4 58 M Bladder Invasive urothelial carcinoma T3N0M0 III Malignant    
45 E5 46 M Bladder Invasive urothelial carcinoma T3N0M0 III Malignant    
46 E6 60 M Bladder Invasive urothelial carcinoma T3N0M0 III Malignant    
47 E7 61 F Bladder Invasive urothelial carcinoma T3N0M0 III Malignant    
48 E8 59 F Bladder Invasive urothelial carcinoma T3N0M0 III Malignant    
49 E9 60 F Bladder Invasive urothelial carcinoma T3N0M0 III Malignant    
50 E10 45 M Bladder Invasive urothelial carcinoma T3N0M0 III Malignant    
51 F1 53 M Bladder Invasive urothelial carcinoma T3N0M0 III Malignant    
52 F2 71 M Bladder Invasive urothelial carcinoma T3N0M0 III Malignant    
53 F3 52 M Bladder Invasive urothelial carcinoma T4N0M0 III Malignant    
54 F4 79 M Bladder Invasive urothelial carcinoma T3N1M0 IV Malignant    
55 F5 64 M Bladder Invasive urothelial carcinoma T3N1M0 IV Malignant    
56 F6 33 M Bladder Invasive urothelial carcinoma T3N1M0 IV Malignant    
57 F7 64 M Bladder Invasive urothelial carcinoma T3N1M0 IV Malignant    
58 F8 40 F Bladder Invasive urothelial carcinoma T3N1M0 IV Malignant    
59 F9 46 F Bladder Invasive urothelial carcinoma T3N2M0 IV Malignant    
60 F10 66 M Bladder Invasive urothelial carcinoma T4N0M0 III Malignant    

TNM Grading

T – Primary tumor
      Tx – Primary tumor cannot be assessed
      T0 – No evidence of primary tumor
      Tis – Carcinoma in situ; intraepithelial or invasion of lamina propria
      T1 – Tumor invades submucosa
      T2 – Tumor invades muscularis propria
      T3 – Tumor invades through muscularis propria into subserosa or into non-peritonealized pericolic or perirectal tissues.
      T4 – Tumor directly invades other organs or structures and/or perforate visceral peritoneum

N – Regional lymph nodes
     Nx – Regional lymph nodes cannot be assessed
     N0 – No regional lymph node metastasis
     N1 – Metastasis in 1 to 3 regional lymph nodes
     N2 – Metastasis in 4 or more regional lymph nodes

M – Distant metastasis
     Mx – Distant metastasis cannot be assessed
     M0 – No distant metastasis
     M1 – Distant metastasis

Stage of Cancer

  • Stage 0 means there’s no cancer, only abnormal cells with the potential to become cancer. This is also called carcinoma in situ.
  • Stage I means the cancer is small and only in one area. This is also called early-stage cancer.
  • Stage II and III mean the cancer is larger and has grown into nearby tissues or lymph nodes.
  • Stage IV means the cancer has spread to other parts of your body. It’s also called advanced or metastatic cancer.