Immunohistochemical Detection System
Immunohistochemistry (IHC) is a technique that uses antibodies—matching molecules—that can seek out, identify and attach themselves to these markers on cells. The antibodies themselves are designed to work with tags that can be detected or seen under a microscope, such as chromogenic or fluorescent staining, which helps to make a precise identification.
Immunohistochemical staining is widely used in the diagnosis of abnormal cells such as those found in cancerous tumors. Specific molecular markers are characteristic of particular cellular events such as proliferation or cell death (apoptosis).Immunohistochemistry is also widely used in basic research to understand the distribution and localization of biomarkers and differentially expressed proteins in different parts of a biological tissue.