Posted on

Heart Tissue Arrays

Please send your request for detailed information and quote to:






CV241Cardiovascular disease tissue array, including TNM and clinical stage, 24 cases/24 cores2424221.00
BC30013aHeart disease and heart tissue array, 18 cases/36 cores, replacing BC300131836292.50
EYE-301(BC30013a)Heart disease and heart tissue array, 18 cases/36 cores, replacing BC300131530292.50
T303Heart tumor and cardiac muscle tissue test array, including TNM and pathology grade, 2 serial sections, 6 cases/24 cores62471.50
HEN241Normal heart tissue array, 24 cases/24 cores2424214.50

TMA Applications:

Routine histology procedures including Immunohistochemistry (IHC) and In Situ Hybridization (ISH)


1) TMA slides were sectioned and stored at 4°C and may not be fresh cut, but still suitable for IHC. Please request fresh cut if experiment involves phospho-specific antibodies, RNA studies, FISH or ISH, etc. A minimum of 3 slides per TMA must be purchased to cover the cost of trimming for fresh sectioning.
2. Most TMA slides were not coated with an extra layer of paraffin (tissue cores can be easily seen on the glass). To prevent tissue detachment during antigen retrieval, unbaked slides must be baked for at least 30 to 120 minutes at 60°C. before putting into xylene for de-paraffinization. Baked slides were sent out baked for 2 hours.

TNM Grading

T – Primary tumor
      Tx – Primary tumor cannot be assessed
      T0 – No evidence of primary tumor
      Tis – Carcinoma in situ; intraepithelial or invasion of lamina propria
      T1 – Tumor invades submucosa
      T2 – Tumor invades muscularis propria
      T3 – Tumor invades through muscularis propria into subserosa or into non-peritonealized pericolic or perirectal tissues.
      T4 – Tumor directly invades other organs or structures and/or perforate visceral peritoneum

N – Regional lymph nodes
     Nx – Regional lymph nodes cannot be assessed
     N0 – No regional lymph node metastasis
     N1 – Metastasis in 1 to 3 regional lymph nodes
     N2 – Metastasis in 4 or more regional lymph nodes

M – Distant metastasis
     Mx – Distant metastasis cannot be assessed
     M0 – No distant metastasis
     M1 – Distant metastasis

Stage of Cancer

  • Stage 0 means there’s no cancer, only abnormal cells with the potential to become cancer. This is also called carcinoma in situ.
  • Stage I means the cancer is small and only in one area. This is also called early-stage cancer.
  • Stage II and III mean the cancer is larger and has grown into nearby tissues or lymph nodes.
  • Stage IV means the cancer has spread to other parts of your body. It’s also called advanced or metastatic cancer.